# Complete Listing ## expand\_more [### Alex K Shalek ](/people/alex-k-shalek) Member of the Harvard-MIT Health Sciences and Technology Faculty The interdisciplinary research in the Shalek Lab aims to create and implement new approaches to elucidate cellular and molecular features that inform tissue-level function and dysfunction across the spectrum of human health and disease. This encompasses... ![shalek_alex.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/shalek_alex.jpg?itok=xOLKNXNG) [### Alex Toker ](/people/alex-toker) Professor of Pathology The major focus of our laboratory is to investigate the cell and molecular biology of cancer, with a focus on the PI 3-Kinase and AKT signaling pathway in cancer. We have investigated the regulation and function of the Akt/PKB and SGK protein kinases... ![toker_alex.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/toker_alex.jpg?itok=MXcCAT7f) [### Amy J. Wagers ](/people/amy-j-wagers) [amy\_wagers@harvard.edu](mailto:amy_wagers@harvard.edu)Forst Family Professor of Stem Cell and Regenerative Biology The broad interest of the WAGERS LAB is to identify and analyze tissue-specific stem cell populations in adult animals. This work focuses on understanding the factors controlling the migration and expansion of bone marrow-derived and blood-forming... person [### Andrea I. McClatchey ](/people/andrea-i-mcclatchey) Professor of Pathology The vast array of forms and functions exhibited by different cell types is made possible by the organization of specialized domains within the cell cortex. The overarching goal of our laboratory is to understand how the organization of protein complexes... ![mcclatchey.png](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/2024-09/mcclatchey.png?itok=GteHuaUP) [### Antoine E. Karnoub ](/people/antoine-e-karnoub) Associate Professor of Pathology Our laboratory at the Center for Life Sciences is interested in understanding the heterotypic crosstalk that operates between the epithelial and the stromal compartments within carcinomas, with particular emphasis on how these interactions influence... ![karnoub_antoine.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/karnoub_antoine.jpg?itok=teADsaKd) [### Bruce Michael Spiegelman ](/people/bruce-michael-spiegelman) [bruce\_spiegelman@dfci.harvard.edu](mailto:bruce_spiegelman@dfci.harvard.edu)Stanley J. Korsmeyer Professor of Cell Biology and Medicine The overall theme of our lab is the regulation of energy homeostasis in mammalian systems, with special reference to adipose and muscle tissues. While we have long been interested in diabetes and obesity, our current interests extend to muscle disorders... person [### Carla Kim ](/people/carla-kim) BCH Professor of Pediatrics in the Field of Regenerative Medicine, Professor of Genetics The Kim Laboratory has pioneered the use of stem cell biology approaches for the study of adult lung progenitor cells and lung cancer. Through a combination of mouse genetics and cell biology, we have developed tools to identify and characterize cells... ![kim_carla.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/kim_carla.jpg?itok=x8N5Q_EO) [### Christian Dibble ](/people/christian-dibble) Assistant Professor of Pathology The Dibble Lab is focused on understanding the regulatory relationship between cellular signaling and metabolic pathways. In particular, we are interested in discovering new mechanisms through which insulin and growth factor stimulated signaling pathways... person [### Cigall Kadoch ](/people/cigall-kadoch) [cigall\_kadoch@dfci.harvard.edu](mailto:cigall_kadoch@dfci.harvard.edu)Associate Professor, Department of Pediatric Oncology Our laboratory research program is centered in understanding the structure and function of ATP-dependent chromatin remodeling complexes, with emphasis on the mammalian SWI/SNF (mSWI/SNF or BAF) family of assemblies. Using a multidisciplinary set of... ![kadoch_cigall.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/kadoch_cigall.jpg?itok=fVcHwhXO) [### Daniel Arie Haber ](/people/daniel-arie-haber) Kurt J. Isselbacher/Peter D. Schwartz Professor of Oncology Our laboratory is interested in the genetics of human cancer. Current projects include the use of a microfluidic device to capture circulating tumor cells (CTCs) and its application in molecular-directed therapy and in the study of human cancer metastasis... person [### David Alan Frank ](/people/david-alan-frank) [david\_frank@dfci.harvard.edu](mailto:david_frank@dfci.harvard.edu)Associate Professor of Medicine Our group focuses on the intracellular signaling events that control the growth and differentiation of normal and malignant cells. Extracellular stimuli lead to a cascade of events which culminates in the regulation of gene expression. It is the... ![frank_david.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/frank_david.jpg?itok=TLmW655p) [### David E. Fisher ](/people/david-e-fisher) Edward Wigglesworth Professor of Dermatology Our group studies cell death/proliferation signals in relation to development and disease, particularly in skin cancer. We attempt to understand critical modes of cell homeostasis with a goal of molecular targeted therapy as well as prevention of melanoma... ![fisher_david.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/fisher_david.jpg?itok=tPuZjurq) [### David E. Golan ](/people/david-e-golan) Dean for Basic Science and Graduate Education Our goals are to understand the molecular interactions controlling protein and lipid mobility and distribution in cell membranes, the roles these mechanisms play in interactions between cells, and the relationships between derangements in these mechanisms... ![golan_david.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/golan_david.jpg?itok=CBx15n4L) [### David M. Langenau ](/people/david-m-langenau) Professor of Pathology The Langenau laboratory research focus is to uncover relapse mechanisms that enhance growth and tumor propagating cell frequency in pediatric cancer. Utilizing zebrafish models of T-cell acute lymphoblastic leukemia (T-ALL) and embryonal rhabdomysoarcoma... ![langenau_david.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/langenau_david.jpg?itok=CLij5uKW) [### David Steven Pellman ](/people/david-steven-pellman) [David\_Pellman@dfci.harvard.edu](mailto:David_Pellman@dfci.harvard.edu)Margaret M. Dyson Professor of Pediatric Oncology Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range of approaches including genetics, functional genomics, biochemistry and live cell imaging. There are... ![pellman_david.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/pellman_david.jpg?itok=LBwGccxn) [### David Weinstock ](/people/david-weinstock) [DavidM\_Weinstock@dfci.harvard.edu](mailto:DavidM_Weinstock@dfci.harvard.edu)Professor of Medicine The Weinstock laboratory uses a variety of in vitro and in vivo techniques to identify and target novel oncogene alterations directly from hematologic malignancies and elucidate mechanisms of aberrant DNA repair within malignant and nonmalignant stem... ![weinstock_david.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/weinstock_david.jpg?itok=Gz4yMY3g) [### Ethan Garner ](/people/ethan-garner) Professor of Molecular and Cellular Biology The focus of our lab is to understand how small collections of genes, operating at local length scales, can establish order at long range distances to create overall cell shape, make the cell divide, segregate cargo within the cell, and create spatial... ![Ethan Garner](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/ethan_garner-lg.jpg?itok=XFmxtl43) [### Fernando D. Camargo ](/people/fernando-d-camargo) Professor of Stem Cell and Regenerative Biology The Camargo laboratory focuses on the study of adult stem cell biology, organ size regulation, and cancer. Despite fantastic progress in developmental biology research over the past decade, one aspect of development and tissue homeostasis for which very... person [### Francesca Gazzaniga ](/people/francesca-gazzaniga) Assistant Professor of Pathology Gut microbiota – the trillions of bacteria, fungi, viruses, and archaea that reside in our gut – contain a dynamic arsenal of products that can protect from or contribute to disease. Diet, medication, exercise, and disease impact the composition of the... ![gazzaniga_francesca.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/gazzaniga_francesca.jpg?itok=selSJDw4) [### Frank John Slack ](/people/frank-john-slack) Shields Warren-Mallinckrodt Professor of Medical Research My lab has pioneered various aspects of the microRNA field and continues to make important contributions to this aspect of post-transcriptional control of gene regulation in stem cell development, cancer and aging. For example we are co-discoverers of the... ![slack_frank.jpg](/sites/g/files/omnuum5431/files/styles/hwp_4_5__690x865/public/landrycancerbio/files/slack_frank.jpg?itok=xaVEFmHK) - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [3](?page=2 "Go to page 3") - [4](?page=3 "Go to page 4") - [ Next page chevron\_right ](?page=1 "Go to next page")