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X-WR-CALNAME;VALUE=TEXT:DF/HCC Seminars in Oncology Series with Stefani Spranger
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SUMMARY:DF/HCC Seminars in Oncology Series with Stefani Spranger
DESCRIPTION:<p>	<strong>Stefani Spranger, Ph.D.</strong><br>Assistant Professor of Biology, Koch Institute for Integrative Cancer Research at MIT</p><p>	 </p><p>	"The goal of the Spranger lab is to understand how a range of tumor cell-intrinsic, tissue-specific and environmental factors directly impact the interaction between the cancer and the immune system. Cancer immunotherapies, first and foremost checkpoint blockade therapy (anti-CTLA4 and anti-PD-1/PD-L1), have revolutionized cancer treatment. Despite these advances only a fraction of cancer patients responds to immunotherapeutic interventions. Even for cancer types that typically show high response rates, only a fraction of patients respond. We aim to understand which tumor cell-intrinsic, tissue-macroenvironmental and environmental factors mediate resistance mechanisms against immunotherapy by affecting T cell infiltration into tumors."</p><p>	 </p>
LOCATION:Yawkey 308
STATUS:CONFIRMED
DTSTART:20171219T170000Z
DTEND:20171219T180000Z
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