#  Roz Segal 

Dean for Graduate Education

Professor of Neurobiology

she/her/hers

 

 

 



 person 

 location\_on Dana Farber Cancer Institute 360 Longwood Avenue LC-6314 Boston, MA 02215 

 smartphone [617-432-1824](tel:617-432-1824) 

 email [roz\_segal@hms.harvard.edu](mailto:roz_segal@hms.harvard.edu) 

 laptop\_windows [Lab website](https://segallab.dana-farber.org/) 

 laptop\_windows [Publications](https://pubmed.ncbi.nlm.nih.gov/?term=Rosalind+Segal) 

 

 



 

 Schedule  
On Campus Monday - Thursday  
Remote on Friday

 Research in the Segal Lab is at the interface of neurobiology and cancer biology. We address the interactions between the nervous system and cancers, including the contributions of the nervous system to tumor micro-environment, and the responses of the nervous system to invasive cancers and to cancer treatment. We use sophisticated compartmented culture systems to identify the role of axonal transport in growth factor signaling initiated by tumor cells, and to examine the mechanism of axonal survival and degeneration in response to chemotherapy. Our published work has focused on mechanisms regulating axonal transport and local protein synthesis in the axons. We build on these studies to develop novel therapies for Chemotherapy induced peripheral neuropathy and other neurodegenerative disorders. Other projects in the lab have pioneered new approaches for propagating pediatric brain tumors in order to evaluate targeted therapies and combination therapies, work that has enabled these therapies to advance to clinical trials.



 

 

 





 

 

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