Complete Listing
Alex K Shalek
shalek@mit.eduMember of the Harvard-MIT Health Sciences and Technology Faculty
The interdisciplinary research in the Shalek Lab aims to create and implement new approaches to elucidate cellular and molecular features that inform tissue-level function and dysfunction across the spectrum of human health and disease. This encompasses...
Alex Toker
atoker@bidmc.harvard.eduProfessor of Pathology
The major focus of our laboratory is to investigate the cell and molecular biology of cancer, with a focus on the PI 3-Kinase and AKT signaling pathway in cancer. We have investigated the regulation and function of the Akt/PKB and SGK protein kinases...
Amy J. Wagers
amy_wagers@harvard.eduForst Family Professor of Stem Cell and Regenerative Biology
The broad interest of the WAGERS LAB is to identify and analyze tissue-specific stem cell populations in adult animals. This work focuses on understanding the factors controlling the migration and expansion of bone marrow-derived and blood-forming...
Andrea I. McClatchey
mcclatch@helix.mgh.harvard.eduProfessor of Pathology
The vast array of forms and functions exhibited by different cell types is made possible by the organization of specialized domains within the cell cortex. The overarching goal of our laboratory is to understand how the organization of protein complexes...
Antoine E. Karnoub
akarnoub@bidmc.harvard.eduAssociate Professor of Pathology
Our laboratory at the Center for Life Sciences is interested in understanding the heterotypic crosstalk that operates between the epithelial and the stromal compartments within carcinomas, with particular emphasis on how these interactions influence...
Bruce Michael Spiegelman
bruce_spiegelman@dfci.harvard.eduStanley J. Korsmeyer Professor of Cell Biology and Medicine
The overall theme of our lab is the regulation of energy homeostasis in mammalian systems, with special reference to adipose and muscle tissues. While we have long been interested in diabetes and obesity, our current interests extend to muscle disorders...
Carla Kim
carla.kim@childrens.harvard.eduBCH Professor of Pediatrics in the Field of Regenerative Medicine, Professor of Genetics
The Kim Laboratory has pioneered the use of stem cell biology approaches for the study of adult lung progenitor cells and lung cancer. Through a combination of mouse genetics and cell biology, we have developed tools to identify and characterize cells...
Christian Dibble
ccdibble@bidmc.harvard.eduAssistant Professor of Pathology
The Dibble Lab is focused on understanding the regulatory relationship between cellular signaling and metabolic pathways. In particular, we are interested in discovering new mechanisms through which insulin and growth factor stimulated signaling pathways...
Cigall Kadoch
cigall_kadoch@dfci.harvard.eduAssociate Professor, Department of Pediatric Oncology
Our laboratory research program is centered in understanding the structure and function of ATP-dependent chromatin remodeling complexes, with emphasis on the mammalian SWI/SNF (mSWI/SNF or BAF) family of assemblies. Using a multidisciplinary set of...
Daniel Arie Haber
dhaber@mgh.harvard.eduKurt J. Isselbacher/Peter D. Schwartz Professor of Oncology
Our laboratory is interested in the genetics of human cancer. Current projects include the use of a microfluidic device to capture circulating tumor cells (CTCs) and its application in molecular-directed therapy and in the study of human cancer metastasis...
David Alan Frank
david_frank@dfci.harvard.eduAssociate Professor of Medicine
Our group focuses on the intracellular signaling events that control the growth and differentiation of normal and malignant cells. Extracellular stimuli lead to a cascade of events which culminates in the regulation of gene expression. It is the...
David E. Fisher
dfisher3@partners.orgEdward Wigglesworth Professor of Dermatology
Our group studies cell death/proliferation signals in relation to development and disease, particularly in skin cancer. We attempt to understand critical modes of cell homeostasis with a goal of molecular targeted therapy as well as prevention of melanoma...
David E. Golan
dgolan@hms.harvard.eduDean for Basic Science and Graduate Education
Our goals are to understand the molecular interactions controlling protein and lipid mobility and distribution in cell membranes, the roles these mechanisms play in interactions between cells, and the relationships between derangements in these mechanisms...
David M. Langenau
dlangenau@partners.orgProfessor of Pathology
The Langenau laboratory research focus is to uncover relapse mechanisms that enhance growth and tumor propagating cell frequency in pediatric cancer. Utilizing zebrafish models of T-cell acute lymphoblastic leukemia (T-ALL) and embryonal rhabdomysoarcoma...
David Steven Pellman
David_Pellman@dfci.harvard.eduMargaret M. Dyson Professor of Pediatric Oncology
Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range of approaches including genetics, functional genomics, biochemistry and live cell imaging. There are...
David Weinstock
DavidM_Weinstock@dfci.harvard.eduProfessor of Medicine
The Weinstock laboratory uses a variety of in vitro and in vivo techniques to identify and target novel oncogene alterations directly from hematologic malignancies and elucidate mechanisms of aberrant DNA repair within malignant and nonmalignant stem...
Ethan Garner
egarner@g.harvard.eduProfessor of Molecular and Cellular Biology
The focus of our lab is to understand how small collections of genes, operating at local length scales, can establish order at long range distances to create overall cell shape, make the cell divide, segregate cargo within the cell, and create spatial...
Fernando D. Camargo
fernando.camargo@childrens.harvard.eduProfessor of Stem Cell and Regenerative Biology
The Camargo laboratory focuses on the study of adult stem cell biology, organ size regulation, and cancer. Despite fantastic progress in developmental biology research over the past decade, one aspect of development and tissue homeostasis for which very...
Francesca Gazzaniga
fgazzaniga@mgh.harvard.eduAssistant Professor of Pathology
Gut microbiota – the trillions of bacteria, fungi, viruses, and archaea that reside in our gut – contain a dynamic arsenal of products that can protect from or contribute to disease. Diet, medication, exercise, and disease impact the composition of the...
Frank John Slack
fslack@bidmc.harvard.eduShields Warren-Mallinckrodt Professor of Medical Research
My lab has pioneered various aspects of the microRNA field and continues to make important contributions to this aspect of post-transcriptional control of gene regulation in stem cell development, cancer and aging. For example we are co-discoverers of the...
