Complete Listing
Mario L. Suvà
Suva.Mario@mgh.harvard.eduAssociate Professor of Pathology
My laboratory is focused on the biology of brain tumors, in particular glioblastoma and oligodendroglioma. My group is dissecting how cellular heterogeneity and plasticity contribute to tumor cell properties. We study primary human samples up to single...
Marsha A Moses
marsha.moses@childrens.harvard.eduJulia Dyckman Andrus Professor of Surgery
Dr. Marsha A. Moses is the Julia Dyckman Andrus Professor at Harvard Medical School and the Director of the Vascular Biology Program at Boston Children's Hospital. She is internationally recognized for her significant contributions to our understanding of...
Martin Nowak
martin_nowak@harvard.eduProfessor of Biology and Mathematics
Martin Nowak is fascinated by all questions of mathematical biology and regrets that he can work only on some. He initiated the field of virus dynamics which is the mathematical study of virus infections. He contributed to the long-standing problem of...
Matthew Langer Meyerson
matthew_meyerson@dfci.harvard.eduProfessor of Genetics and Medicine
We strive to discover genomic and infectious causes for human cancers. We then seek to apply these discoveries to understand mechanisms of cancer pathogenesis, and to improve cancer diagnosis and treatment. A particular focus is lung cancer pathogenesis...
Michael Joseph Eck
eck@crystal.harvard.eduProfessor of Biological Chemistry and Molecular Pharmacology
We study cell signaling and regulation of the actin cytoskeleton using structural and biochemical approaches. We seek to understand fundamental signaling mechanisms and principles by dissecting out and determining the structure of “regulatory modules” –...
Mikael Pittet
mpittet@mgh.harvard.eduAssociate Professor of Radiology
My laboratory focuses on uncovering knowledge gaps on the interactions between the immune system and cancer and defining immunotherapies that are effective against a broad range of tumors. To do so, we study various immune cells, including cytotoxic T...
Mo R. Motamedi
mmotamedi@hms.harvard.eduAssistant Professor of Medicine
We are interested in the mechanisms by which cells regulate their gene expression patterns stably and heritably. Stable inheritance of distinct transcriptional states that persist through numerous cell divisions is critical for the formation of cellular...
Myles Brown
myles_brown@dfci.harvard.eduEmil Frei III Professor of Medicine
The primarily focus of the work in my laboratory is the molecular understanding of the action of steroid hormone receptors and their role in human cancer. We were the first to identify the p160 class of steroid receptor coactivators and to show that...
Naama Kanarek
naama.kanarek@childrens.harvard.eduAssistant Professor of Pathology
The Kanarek Laboratory is interested in folate metabolism. It is surprising that this essential vitamin, so famous for its key role in development, hematopoiesis and cancer progression, is still a mystery when it comes to its cellular and whole-body...
Nada Y. Kalaany
Nada.Kalaany@childrens.harvard.eduAssociate Professor in Pediatrics
How nutrient uptake and utilization is altered in cancer, how the host systemic metabolic state can influence these alterations and in turn, get affected by tumor growth and metabolism, are major focus areas in our lab. Altered metabolism is a hallmark of...
Nika Danial
nika_danial@dfci.harvard.eduAssociate Professor in the Department of Molecular Metabolism
Our lab investigates the metabolic mechanisms that regulate cellular and organismal adaptation to physiologic and pathologic stress conditions. Within this context, we study fundamental aspects of metabolic biology, including causes and consequences of...
Norbert Perrimon
perrimon@receptor.med.harvard.eduJames Stillman Professor of Developmental Biology
Physiological and Regenerative Homeostasis in Drosophila The central objective of developmental biology is to understand how organisms grow to adulthood. In the past 30 years, studies using genetically tractable model systems have led to a detailed...
Pasi A. Jänne
pjanne@partners.orgProfessor of Medicine
The focus of my research is to understand mechanisms of sensitivity and resistance to kinase inhibitors and to translate laboratory based observations into therapeutic treatments for patients with cancer. To achieve this goal we have taken a multifaceted...
Pere B. Puigserver
pere_puigserver@dfci.harvard.eduProfessor of Cell Biology
Our lab investigates broad aspects of fundamental metabolic and energetic processes in mammals that are necessary for cell survival and specific biological function. We combine and apply a variety of biochemical, cellular, genetic, chemical biology...
Piotr Sicinski
peter_sicinski@dfci.harvard.eduProfessor of Genetics
Our laboratory studies the role of cell cycle machinery in normal cell proliferation and in oncogenesis using mouse genetic, genomic, proteomic and systems biology approaches. Cyclins and their catalytic partners, cyclin-dependent kinases (CDKs) are...
Rakesh K. Jain
jain@steele.mgh.harvard.eduA. Werk Cook Professor of Radiation Oncology (Tumor Biology)
The overall goal of our research is to understand the role of the tumor microenvironment, including the tumor vasculature and matrix, in tumor growth and response to therapy, to develop novel strategies to manipulate the tumor microenvironment, and to...
Ralph Scully
rscully@bidmc.harvard.eduProfessor of Medicine
We study the relationships between mammalian double strand break (DSB) repair, genomic instability and cancer. Two major pathways contribute to DSB repair: homologous recombination (HR) and non-homologous end joining (NHEJ). Each plays a key role in...
Randall Wharton King
randy_king@hms.harvard.eduHarry C. McKenzie Professor of Cell Biology
Our goal is to develop new approaches for treating human disease, based on our understanding of fundamental cell biological principles. We start by identifying new compounds that perturb complex cellular pathways, and then use the compounds as tools to...
Raul Mostoslavsky
rmostoslavsky@mgh.harvard.eduLaurel Schwartz Professor of Medicine in the Field of Oncology
Cells need to accurately maintain their nuclear DNA in order to function properly. Indeed, defects in DNA integrity are associated with cancer, aging, and immunodeficiency. Therefore, numerous DNA repair systems in mammalian cells function to endow us...
Robert E. Kingston
kingston@molbio.mgh.harvard.eduProfessor of Genetics
To maintain the differentiated tissues in any organism, cell-type specific genes must remain ‘on' for the lifetime of the organism in one cell type, and ‘off' for the lifetime of the organism in other cells. Thus the same gene, with the same primary DNA...
